Title: KSUMC Evidence-Based Clinical Practice Guideline for Sedation and Analgesia in Critically ill Adult Patients in Intensive Care Units
Edition: Adapted
Classification: Standard guideline
Field: Comprehensive guideline
Countries and regions: Saudi Arabia
Guidelines users: Physicians and Nurses in Intensive Care Units Respiratory Therapists ICU Clinical Pharmacists
Evidence classification method: The description of the methodology for the production of this adapted CPG can be fulfilled by utilizing the King Saud University (KSU) Modified ADAPTE method. This CPG formal adaptation method included three phases (setup, adaptation, and finalization), nine modules, and 24 steps with modifications in the steps and tools to suit the local general healthcare setting in Saudi Arabia. Overall, the steps of CPG adaptation included the selection of the health topic, formulation of the CPG adaptation working group, identification of health questions using the PIPOH model, searching and selecting Source CPGs with clear inclusion and exclusion criteria, quality assessment of included Source CPGs by using the Appraisal of Guidelines for Research and Evaluation (AGREE) II Instrument, assessment of the currency of the selected Source CPG, drafting of the adapted CPG, external review and consultation process, finalization of the adapted CPG with a set of implementation tools, declaration of conflicts of interests, and finally a plan for review and update. For further details on the specific modifications in steps and tools, refer to the article by Amer et al. 2019 (https://doi.org/10.1111/jep.12927).
Development unit: King Saud University Medical City, Riyadh, Saudi Arabia (KSUMC)
Registration time: 2022-03-19
Registration number: IPGRP-2022CN158
Purpose of the guideline: To recommend best practices for assessing, treating, and preventing pain, agitation, and delirium to improve clinical outcomes of critically ill adult patients in intensive care units.