| Title： | Chinese Guideline on Risk Management of Cognitive Decline and Dementia in the General Public |
| Edition： | Original |
| Classification： | Standard guideline |
| Field： | Prevention |
| Countries and regions： | China |
| Guidelines users： | The target audience of this guideline is the general population in all regions and all ethnic groups of China, especially adults at high risk of cognitive decline and dementia. |
| Evidence classification method： | The GRADE method will be used to evaluate the quality of evidence related to cognitive decline and dementia. According to the GRADE method, the quality of evidence will be divided into high quality, moderate quality, low quality, and very low quality. In the evidence grading process, there are five downgrading factors: limitations, imprecision, inconsistency, indirectness, and publication bias, and three upgrading factors: large effect size, dose-response relationship, and possible confounders (negative bias). |
| Development unit： | Chinese Health RIsk MAnagement Collaboration (CHRIMAC)‑Dementia Group |
| Registration time: | 2023-11-27 |
| Registration number： | PREPARE-2023CN960 |
| Purpose of the guideline: | Cognitive decline and dementia is a current public health problem that seriously affects the quality of life, and imposes a heavy economic burden on patients' families and society. The clinical treatment effect of dementia is minimal, but changing the modifiable risk factors can effectively prevent the disease. This guideline systematically reviews and summarizes relevant evidence on the prevention of dementia and cognitive decline in the general population and high-risk groups, and forms a public guide for risk management, thereby guiding the prevention and control of cognitive decline and dementia. |
