Title: The Egyptian Adapted Guidelines for the Diagnosis,Treatment and Prevention of Thrombosis in the Pediatric Age Group
Edition: Adapted
Classification: Standard guideline
Field: Comprehensive guideline
Countries and regions: Egypt
Guidelines users: Primary health care physicians at the MOH General practitioners Family medicine specialists Pediatricians Hematologists, Oncologists Neonatologists, intensive care specialists, surgeons, neurologists Nurses Medical students
Evidence classification method: The description of the methodology for the production of this adapted CPG can be fulfilled by utilizing the ‘Adapted ADAPTE’ method. This CPG formal adaptation method includes three phases (setup, adaptation, and finalization), nine modules, and 24 steps with modifications in the steps and tools to suit the local general healthcare setting in Egypt. Overall, the steps of CPG adaptation includes the selection of the high-priority health topic, formulation of the CPG adaptation working group, identification of health questions using the PIPOH model, searching and selecting the source original CPGs with clear inclusion and exclusion criteria, quality assessment of included source CPGs by using the Appraisal of Guidelines for Research and Evaluation (AGREE) II Instrument, assessment of the currency of the selected source CPGs, drafting of the adapted CPG, external review and consultation process, finalization of the adapted CPG with a set of implementation tools, declaration of conflicts of interests, and finally a plan for review and update. For further details on the specific modifications in steps and tools, refer to the article https://doi.org/10.1111/jep.12479].
Development unit: Egyptian Pediatric Clinical Practice Guidelines Committee (EPG), Egypt
Registration time: 2023-11-23
Registration number: PREPARE-2023CN908
Purpose of the guideline: Provide an evidence-based document for the 1. Identification of neonates, infants, children and adolescents at high risk of thrombosis. 2. Diagnostic approaches in the target population. 3. Management of thrombosis in the target population. 4. Prevention of thrombosis in the target population